Two new triterpenoid-chromone hybrids from the rhizomes ofActaea cimicifugaL. (syn.Cimicifuga foetidaL.) and their cytotoxic activities

doi:10.1080/14786419.2020.1775228

KIB OpenIR

	Two new triterpenoid-chromone hybrids from the rhizomes ofActaea cimicifugaL. (syn.Cimicifuga foetidaL.) and their cytotoxic activities
	Shi,Qiang-Qiang ; Gao,Ya ; Lu,Jing ; Zhou,Lin ; Qiu,Ming-Hua
	2021
Source Publication	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
Volume	36 Issue:1 Pages:193-199
Abstract	Two new triterpenoid-chromone hybrids, cimitriteromones H (1) and I (2), along with two known analogues (3,4) were isolated from the phytochemical research on then-butyl alcohol extracts ofActaea cimicifugarhizomes. The new compounds were elucidated by spectroscopic experiments and chemical method. The cytotoxic activities of the isolated compounds were tested on A-549/Taxol cell line. Cimitriteromone I (2) showed cytotoxicity with IC(50)value of 27.14 +/- 1.38 mu M comparable to positive control group cisplatin (IC(50)value of 25.80 +/- 1.15 mu M).
Keyword	Actaea cimicifuga Triterpenoid-chromone hybrid Cytotoxicity BLACK COHOSH ROOTS CONSTITUENTS GLYCOSIDES DAHURICA
DOI	10.1080/14786419.2020.1775228
WOS ID	WOS:000542762600001
Citation statistics
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/73334
Collection	中国科学院昆明植物研究所
Affiliation	1.[Shi, Qiang-Qiang 2.Gao, Ya 3.Lu, Jing 4.Zhou, Lin 5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China 6.Univ Chinese Acad Sci, Beijing, Peoples R China 7.Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming, Yunnan, Peoples R China
Recommended Citation GB/T 7714	Shi,Qiang-Qiang,Gao,Ya,Lu,Jing,et al. Two new triterpenoid-chromone hybrids from the rhizomes ofActaea cimicifugaL. (syn.Cimicifuga foetidaL.) and their cytotoxic activities[J]. NATURAL PRODUCT RESEARCH,2021,36(1):193-199.
APA	Shi,Qiang-Qiang,Gao,Ya,Lu,Jing,Zhou,Lin,&Qiu,Ming-Hua.(2021).Two new triterpenoid-chromone hybrids from the rhizomes ofActaea cimicifugaL. (syn.Cimicifuga foetidaL.) and their cytotoxic activities.NATURAL PRODUCT RESEARCH,36(1),193-199.
MLA	Shi,Qiang-Qiang,et al."Two new triterpenoid-chromone hybrids from the rhizomes ofActaea cimicifugaL. (syn.Cimicifuga foetidaL.) and their cytotoxic activities".NATURAL PRODUCT RESEARCH 36.1(2021):193-199.

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