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(+/-)-Stagonosporopsin A, stagonosporopsin B and stagonosporopsin C, antibacterial metabolites produced by endophytic fungus Stagonosporopsis oculihominis
Wang,Ju-Tao; Li,Hui-Yuan; Rao,Rao; Yue,Jing-Yi; Wang,Guo-Kai; Yu,Yang
2021
发表期刊PHYTOCHEMISTRY LETTERS
ISSN1874-3900
卷号45页码:157-160
摘要A successive investigation of the endophytic fungus Stagonosporopsis oculihominis isolated from Dendrobium huoshanense led to the discovery of two undescribed secondary metabolites, (+/-)-stagonosporopsin A and stagonosporopsin B, and a new natural product, stagonosporopsin C. (+/-)-stagonosporopsin A is a pair of enantiomer. The structures of the isolated compounds, including their absolute configurations, were elucidated based on extensive spectroscopic analyses, electronic circular dichroism (ECD) calculations and X-ray diffraction. Stagonosporopsin C exhibited moderate inhibitory activity against Staphylococcus aureus subsp. aureus ATCC29213 with an MIC50 value of 41.3 mu M.
关键词Endophytic fungus Stagonosporopsis oculihominis Enantiomer Spectroscopic analyses Antibacterial activity
DOI10.1016/j.phytol.2021.08.017
WOS记录号WOS:000729961300028
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/73263
专题中国科学院昆明植物研究所
作者单位1.Anhui Univ Chinese Med, Sch Pharm, Hefei 230012, Peoples R China
2.Anhui Prov Key Lab Res Dev Chinese Med, Hefei 230012, Peoples R China
3.Anhui Univ Chinese Med, Inst Neurol, Hefei 230061, Peoples R China
4.Wuhu Inst Technol, Wuhu 241006, Peoples R China
5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resource West Chi, Kunming 650201, Yunnan, Peoples R China
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Wang,Ju-Tao,Li,Hui-Yuan,Rao,Rao,et al. (+/-)-Stagonosporopsin A, stagonosporopsin B and stagonosporopsin C, antibacterial metabolites produced by endophytic fungus Stagonosporopsis oculihominis[J]. PHYTOCHEMISTRY LETTERS,2021,45:157-160.
APA Wang,Ju-Tao,Li,Hui-Yuan,Rao,Rao,Yue,Jing-Yi,Wang,Guo-Kai,&Yu,Yang.(2021).(+/-)-Stagonosporopsin A, stagonosporopsin B and stagonosporopsin C, antibacterial metabolites produced by endophytic fungus Stagonosporopsis oculihominis.PHYTOCHEMISTRY LETTERS,45,157-160.
MLA Wang,Ju-Tao,et al."(+/-)-Stagonosporopsin A, stagonosporopsin B and stagonosporopsin C, antibacterial metabolites produced by endophytic fungus Stagonosporopsis oculihominis".PHYTOCHEMISTRY LETTERS 45(2021):157-160.
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