Knowledge Management System of Kunming Institute of Botany,CAS
| Chemical synthesis of marine saponins | |
| Xiao,Guozhi; Shao,Xiaofei; Zhu,Dapeng; Yu,Biao | |
| 2019 | |
| Source Publication | NATURAL PRODUCT REPORTS
 |
| ISSN | 0265-0568 |
| Volume | 36Issue:5Pages:769-787 |
| Abstract | Saponins are characteristic metabolites of starfish and sea cucumbers, and occasionally are also found in sponges, soft coral, and small fish. These steroid or triterpenoid glycosides often show remarkable biological and pharmacological activities, such as antifungal, antifouling, shark repellent, antitumor and anti- inflammatory activities. Over one thousand marine saponins have been characterized; the majority of them can be categorized into three major structural types, i.e., asterosaponins, polyhydroxysteroid glycosides, and holostane glycosides. Thus far, only 12 marine saponins have been synthesized; those representing the major types were successfully synthesized recently. The syntheses involve preparation of the aglycones from the terrestrial steroid or triterpene materials, installation of the carbohydrate units, and manipulation of the protecting groups. Herein, we provide a comprehensive review on these syntheses. |
| DOI | 10.1039/c8np00087e |
| Indexed By | SCI |
| WOS ID | WOS:000468788800003 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/71105 |
| Collection | 中国科学院昆明植物研究所 |
| Recommended Citation GB/T 7714 | Xiao,Guozhi,Shao,Xiaofei,Zhu,Dapeng,et al. Chemical synthesis of marine saponins[J]. NATURAL PRODUCT REPORTS,2019,36(5):769-787. |
| APA | Xiao,Guozhi,Shao,Xiaofei,Zhu,Dapeng,&Yu,Biao.(2019).Chemical synthesis of marine saponins.NATURAL PRODUCT REPORTS,36(5),769-787. |
| MLA | Xiao,Guozhi,et al."Chemical synthesis of marine saponins".NATURAL PRODUCT REPORTS 36.5(2019):769-787. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Xiao-2019-Chemical s（3812KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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