KIB OpenIR
Chemical synthesis of marine saponins
Xiao,Guozhi; Shao,Xiaofei; Zhu,Dapeng; Yu,Biao
2019
Source PublicationNATURAL PRODUCT REPORTS
ISSN0265-0568
Volume36Issue:5Pages:769-787
AbstractSaponins are characteristic metabolites of starfish and sea cucumbers, and occasionally are also found in sponges, soft coral, and small fish. These steroid or triterpenoid glycosides often show remarkable biological and pharmacological activities, such as antifungal, antifouling, shark repellent, antitumor and anti- inflammatory activities. Over one thousand marine saponins have been characterized; the majority of them can be categorized into three major structural types, i.e., asterosaponins, polyhydroxysteroid glycosides, and holostane glycosides. Thus far, only 12 marine saponins have been synthesized; those representing the major types were successfully synthesized recently. The syntheses involve preparation of the aglycones from the terrestrial steroid or triterpene materials, installation of the carbohydrate units, and manipulation of the protecting groups. Herein, we provide a comprehensive review on these syntheses.
DOI10.1039/c8np00087e
Indexed BySCI
WOS IDWOS:000468788800003
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Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/71105
Collection中国科学院昆明植物研究所
Recommended Citation
GB/T 7714
Xiao,Guozhi,Shao,Xiaofei,Zhu,Dapeng,et al. Chemical synthesis of marine saponins[J]. NATURAL PRODUCT REPORTS,2019,36(5):769-787.
APA Xiao,Guozhi,Shao,Xiaofei,Zhu,Dapeng,&Yu,Biao.(2019).Chemical synthesis of marine saponins.NATURAL PRODUCT REPORTS,36(5),769-787.
MLA Xiao,Guozhi,et al."Chemical synthesis of marine saponins".NATURAL PRODUCT REPORTS 36.5(2019):769-787.
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