First total synthesis of rhuscholide A, glabralide B and denudalide

doi:10.1016/j.tetlet.2019.151059

KIB OpenIR

	First total synthesis of rhuscholide A, glabralide B and denudalide
	Li, Tian-Ze 1; Geng, Chang-An1 ; Chen, Ji-Jun1,2
通讯作者	Chen, Ji-Jun(chenjj@mail.kib.ac.cn)
	2019-09-19
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	60 期号:38 页码:4
摘要	The first total synthesis of rhuscholide A, a benzofuran lactone possessing anti-HIV-1 activity, had been accomplished in 14 linear steps with 10.6% overall yield. In this synthesis, base-mediated phenol ortho-alkylation and piperidine promoted aldol condensation were exploited as key steps. The synthesis was flexible and allowed for the convenient preparation of two analogous natural products glabralide B and denudalide. (C) 2019 Published by Elsevier Ltd.
关键词	Total synthesis Rhuscholide A Glabralide B Denudalide
DOI	10.1016/j.tetlet.2019.151059
收录类别	SCI
语种	英语
WOS记录号	WOS:000488141200015
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/69493
专题	中国科学院昆明植物研究所
通讯作者	Chen, Ji-Jun
作者单位	1.Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Li, Tian-Ze,Geng, Chang-An,Chen, Ji-Jun. First total synthesis of rhuscholide A, glabralide B and denudalide[J]. TETRAHEDRON LETTERS,2019,60(38):4.
APA	Li, Tian-Ze,Geng, Chang-An,&Chen, Ji-Jun.(2019).First total synthesis of rhuscholide A, glabralide B and denudalide.TETRAHEDRON LETTERS,60(38),4.
MLA	Li, Tian-Ze,et al."First total synthesis of rhuscholide A, glabralide B and denudalide".TETRAHEDRON LETTERS 60.38(2019):4.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Li-2019-First total （709KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览请求全文