KIB OpenIR
Application of Metabolomics in the Study of Natural Products.
Zhao, Qi; Zhang, Jia-Le; Li, Fei
2018
Source PublicationNatural products and bioprospecting
ISSN2192-2195
Volume8Issue:4Pages:321-334
AbstractLC-MS-based metabolomics could have a major impact in the study of natural products, especially in its metabolism, toxicity and activity. This review highlights recent applications of metabolomics approach in the study of metabolites and toxicity of natural products, and the understanding of their effects on various diseases. Metabolomics has been employed to study the in vitro and in vivo metabolism of natural compounds, such as osthole, dehydrodiisoeugenol, and myrislignan. The pharmacological effects of natural compounds and extracts were determined using metabolomics technology combined with diseases models in animal, including osthole and nutmeg extracts. It has been demonstrated that metabolomics is a powerful technology for the investigation of xenobiotics-induced toxicity. The metabolism of triptolide and its hepatotoxicity were discussed. LC-MS-based metabolomics has a great potential in the druggability of natural products. The application of metabolomics should be broadened in the field of natural products in the future.
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/64804
Collection中国科学院昆明植物研究所
Recommended Citation
GB/T 7714
Zhao, Qi,Zhang, Jia-Le,Li, Fei. Application of Metabolomics in the Study of Natural Products.[J]. Natural products and bioprospecting,2018,8(4):321-334.
APA Zhao, Qi,Zhang, Jia-Le,&Li, Fei.(2018).Application of Metabolomics in the Study of Natural Products..Natural products and bioprospecting,8(4),321-334.
MLA Zhao, Qi,et al."Application of Metabolomics in the Study of Natural Products.".Natural products and bioprospecting 8.4(2018):321-334.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhao, Qi]'s Articles
[Zhang, Jia-Le]'s Articles
[Li, Fei]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhao, Qi]'s Articles
[Zhang, Jia-Le]'s Articles
[Li, Fei]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhao, Qi]'s Articles
[Zhang, Jia-Le]'s Articles
[Li, Fei]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.