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Two New Alkaloids from Fusarium tricinctum SYPF 7082, an Endophyte from the Root of Panax notoginseng.
Sun, Wen-Jie; Zhu, Hong-Tao; Zhang, Tian-Yuan; Zhang, Meng-Yue; Wang, Dong; Yang, Chong-Ren; Zhang, Yi-Xuan; Zhang, Ying-Jun
2018
Source PublicationNatural products and bioprospecting
ISSN2192-2195
Volume8Issue:5Pages:391-396
Abstract

Panax notoginseng (Araliaceae) is a famous traditional Chinese medicine mainly cultivated in Yunnan and Guangxi provinces of China. Two new alkaloids, rigidiusculamide E (1) and [-(alpha-oxyisohexanoyl-N-methyl-leucyl)2-] (2), together with two known ones, (-)-oxysporidinone (3) and (-)-4,6'-anhydrooxysporidinone (4) were isolated from the mycelia culture of Fusarium tricinctum SYPF 7082, an endophytic fungus obtained from the healthy root of P. notoginseng. Their structures were determined on the basis of extensive spectroscopic analyses. Compounds 1-4 were tested for their inhibitory effects against NO production on Murine macrophage cell line, and the new compound 2 showed significant inhibitory activity on NO production with the IC50 value of 18.10±0.16muM.

Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/64785
Collection中国科学院昆明植物研究所
Recommended Citation
GB/T 7714
Sun, Wen-Jie,Zhu, Hong-Tao,Zhang, Tian-Yuan,et al. Two New Alkaloids from Fusarium tricinctum SYPF 7082, an Endophyte from the Root of Panax notoginseng.[J]. Natural products and bioprospecting,2018,8(5):391-396.
APA Sun, Wen-Jie.,Zhu, Hong-Tao.,Zhang, Tian-Yuan.,Zhang, Meng-Yue.,Wang, Dong.,...&Zhang, Ying-Jun.(2018).Two New Alkaloids from Fusarium tricinctum SYPF 7082, an Endophyte from the Root of Panax notoginseng..Natural products and bioprospecting,8(5),391-396.
MLA Sun, Wen-Jie,et al."Two New Alkaloids from Fusarium tricinctum SYPF 7082, an Endophyte from the Root of Panax notoginseng.".Natural products and bioprospecting 8.5(2018):391-396.
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