Anti-inflammatory furostanol saponins from the rhizomes of Smilax china L

KIB OpenIR

	Anti-inflammatory furostanol saponins from the rhizomes of Smilax china L
	Xie, Yang; Hu, Deng; Zhong, Cheng; Liu, Kai-Fei; Fang, En; Zhang, Ying-Jun; Zhou, Chun; Tian, Li-Wen
	2018
发表期刊	STEROIDS
ISSN	0039-128X
卷号	140 页码:70-76
摘要	Seven new furostanol saponins (1-7), chongrenosides A-G, were isolated from the rhizomes of Smilax china L, together with nine known furostanol saponins (8-16). The structures of the new furostanol saponins (1-7) were elucidated by extensive spectroscopic data analyses (1D and 2D NMR, HRESIMS) and chemical evidence. Compounds 1-6 and 8-16 were evaluated for TNF-alpha mRNA expression inhibitory activity on LPS induced RAW264.7 cells. Of them, 1, 4, 6, and 11 inhibited the TNF-a mRNA expression by 88%, 87%, 67%, and 93%, respectively, at the concentration of 10 mu M.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64671
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Xie, Yang,Hu, Deng,Zhong, Cheng,et al. Anti-inflammatory furostanol saponins from the rhizomes of Smilax china L[J]. STEROIDS,2018,140:70-76.
APA	Xie, Yang.,Hu, Deng.,Zhong, Cheng.,Liu, Kai-Fei.,Fang, En.,...&Tian, Li-Wen.(2018).Anti-inflammatory furostanol saponins from the rhizomes of Smilax china L.STEROIDS,140,70-76.
MLA	Xie, Yang,et al."Anti-inflammatory furostanol saponins from the rhizomes of Smilax china L".STEROIDS 140(2018):70-76.