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Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins
Wang, Liang-Liang; Jiang, Ting; Li, Peng-Hua; Sun, Rou-Jing; Zuo, Zhili
2018
Source PublicationADVANCED SYNTHESIS & CATALYSIS
ISSN1615-4150
Volume360Issue:24Pages:4832-4836
AbstractA variety of enantioenriched 3-N-substituted spirooxindole-dihydroquinazolinones were synthesized by cyclization reactions involving 2-amino-N-substituted benzamides and isatins catalyzed by SPINOL-CPA catalyst in a highly enantioselective manner with excellent ee values (up to 99%) and good yields (up to 99%). So far, this is the first example to directly access this type of chiral pharmaceutically privileged 3-N-substituted dihydroquinazolinone derivatives with a broad substrate scope.
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/64658
Collection中国科学院昆明植物研究所
Recommended Citation
GB/T 7714
Wang, Liang-Liang,Jiang, Ting,Li, Peng-Hua,et al. Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins[J]. ADVANCED SYNTHESIS & CATALYSIS,2018,360(24):4832-4836.
APA Wang, Liang-Liang,Jiang, Ting,Li, Peng-Hua,Sun, Rou-Jing,&Zuo, Zhili.(2018).Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins.ADVANCED SYNTHESIS & CATALYSIS,360(24),4832-4836.
MLA Wang, Liang-Liang,et al."Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins".ADVANCED SYNTHESIS & CATALYSIS 360.24(2018):4832-4836.
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