Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins

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	Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins
	Wang, Liang-Liang; Jiang, Ting; Li, Peng-Hua; Sun, Rou-Jing; Zuo, Zhili
	2018
发表期刊	ADVANCED SYNTHESIS & CATALYSIS
ISSN	1615-4150
卷号	360 期号:24 页码:4832-4836
摘要	A variety of enantioenriched 3-N-substituted spirooxindole-dihydroquinazolinones were synthesized by cyclization reactions involving 2-amino-N-substituted benzamides and isatins catalyzed by SPINOL-CPA catalyst in a highly enantioselective manner with excellent ee values (up to 99%) and good yields (up to 99%). So far, this is the first example to directly access this type of chiral pharmaceutically privileged 3-N-substituted dihydroquinazolinone derivatives with a broad substrate scope.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64658
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Wang, Liang-Liang,Jiang, Ting,Li, Peng-Hua,et al. Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins[J]. ADVANCED SYNTHESIS & CATALYSIS,2018,360(24):4832-4836.
APA	Wang, Liang-Liang,Jiang, Ting,Li, Peng-Hua,Sun, Rou-Jing,&Zuo, Zhili.(2018).Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins.ADVANCED SYNTHESIS & CATALYSIS,360(24),4832-4836.
MLA	Wang, Liang-Liang,et al."Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins".ADVANCED SYNTHESIS & CATALYSIS 360.24(2018):4832-4836.