Antifungal agents from the roots of Cudrania cochinchinensis against candida, cryptococcus, and Aspergillus species
Fukai, T; Yonekawa, M; Hou, AJ; Nomura, T; Sung, HD; Uno, J
2003-08-01
发表期刊JOURNAL OF NATURAL PRODUCTS
卷号66期号:8页码:1118-1120
摘要Bioassay-guided fractionation resulted in the isolation of four antifungal agents from the roots of Cudrania cochinchinensis. Two of these were new compounds, cudraxanthone S [1, 1,3,5,6-tetrahydroxy-2-(1,1dimethyl-2-propenyl)xanthone] and cudraflavanone B (2, 2',4',5,7-tetrahydroxy-6-prenylflavanone). The remaining two compounds were known compounds, toxyloxanthone C (3) and wighteone (4). Among these compounds, 1, 3, and 4 exhibited antifungal activities against Cryptococcus neoformans, Aspergillus fumigatus, and A. nidulans (MICs = 2-8 mug/mL). Compounds 1 and 3 also showed antifungal activity against Candida glabrata (MICs = 4-8 mug/mL).
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np030024u
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000184942300020
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被引频次:35[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5156
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Toho Univ, Sch Pharmaceut Sci, Funabashi, Chiba 2748510, Japan
2.Fundan Univ, Sch Pharm, Shanghai 200032, Peoples R China
3.Acad Sinica, Kunming Inst bot, Lab Phytochem, Kunming 650204, Peoples R China
4.Chiba Univ, RCPFMT, Chuo Ku, Chiba 2608673, Japan
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Fukai, T,Yonekawa, M,Hou, AJ,et al. Antifungal agents from the roots of Cudrania cochinchinensis against candida, cryptococcus, and Aspergillus species[J]. JOURNAL OF NATURAL PRODUCTS,2003,66(8):1118-1120.
APA Fukai, T,Yonekawa, M,Hou, AJ,Nomura, T,Sung, HD,&Uno, J.(2003).Antifungal agents from the roots of Cudrania cochinchinensis against candida, cryptococcus, and Aspergillus species.JOURNAL OF NATURAL PRODUCTS,66(8),1118-1120.
MLA Fukai, T,et al."Antifungal agents from the roots of Cudrania cochinchinensis against candida, cryptococcus, and Aspergillus species".JOURNAL OF NATURAL PRODUCTS 66.8(2003):1118-1120.
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