Two new taxoids from Taxus chinensis | |
Xia, ZH; Peng, LY; Zhao, Y; Xu, G; Zhao, QS; Sun, HD | |
2005 | |
发表期刊 | CHEMISTRY & BIODIVERSITY |
ISSN | 1612-1872 |
卷号 | 2期号:10页码:1316-1319 |
摘要 | Two new taxoids, 2,20-O-diacetyltaxumairol N (1) and 14 beta-hydroxy-10-deacetyl-2-O-debenzoylbacatin III (2), were isolated from the needles and stems of Taxus chinensis. Their structures were determined on the basis of extensive 1D- and 2D-NMR-spectral analysis. Compound 1 showed weak cytotoxicity activity against T-24 (IC50 = 34 mu g/ml) and QGY-7701 (IC50 = 22 mu g/ml) cancer lines. Compound 2 showed no obvious cytotoxicity activity against T-24 (IC50 > 100 mu g/ml) and QGY-7701 (IC50 > 100 mu g/ml) cancer lines. |
关键词 | Oxetane-ring Taxanes Mairei Roots |
学科领域 | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000233147400005 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/4046 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Kunming 650204, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Xia, ZH,Peng, LY,Zhao, Y,et al. Two new taxoids from Taxus chinensis[J]. CHEMISTRY & BIODIVERSITY,2005,2(10):1316-1319. |
APA | Xia, ZH,Peng, LY,Zhao, Y,Xu, G,Zhao, QS,&Sun, HD.(2005).Two new taxoids from Taxus chinensis.CHEMISTRY & BIODIVERSITY,2(10),1316-1319. |
MLA | Xia, ZH,et al."Two new taxoids from Taxus chinensis".CHEMISTRY & BIODIVERSITY 2.10(2005):1316-1319. |
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