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题名: Seven new Lycopodium alkaloids from the aerial parts of Phlegmariurus squarrosus
作者: Li, Ping; Huang, Wen; Zhuo, Jingxian; Guo, Zhiyong; Cao, Wujisiguleng; Xu, Li; Ma, Lijuan; Chen, Ze-E.; Kennelly, Edward J.; Wu, Shi-Biao; Long, Chunlin
刊名: TETRAHEDRON
关键词: Lycopodium alkaloids ; Phlegmariurus squarrosus ; Lycopodiaceae ; Structure elucidation ; Acetylcholinesterase inhibitor
英文摘要: Seven new Lycopodium alkaloids, squarrosusines A-E (1-3, 5 and 6), 8-epilycoposerramine U (4) and squarrosusine F N-exide (7), and 4 related known compounds (8-11) were isolated from the aerial parts of Phlegmariurus squarrosus. The structures of these seven new compounds share a unique heterocyclic C16N-type skeleton. The chemical structures of the new compounds were established through spectroscopic methods, including 2D NMR techniques and mass spectrometry, as well as chemical reaction. The inhibition effects of the isolates against acetylcholinesterase (AChE) were evaluated in vitro. (C) 2015 Elsevier Ltd. All rights reserved.
出版日期: 2015-08-19
卷号: 71, 期号:33, 页码:5308-5314
DOI标识: 10.1016/j.tet.2015.06.012
语种: 英语
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/25076
Appears in Collections:离退休_期刊论文

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