Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009)

doi:10.1080/08820130600992115

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	Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009)
	Taechowisan, Thongchai ; Tuntiwachwuttikul, Pittaya ; Lu, Chunhua ; Shen, Yuemao ; Lumyong, Saisamorn ; Taylor, Walter C.
	2007
发表期刊	IMMUNOLOGICAL INVESTIGATIONS
卷号	36 期号:2 页码:203-211
摘要	This research was undertaken to test the in vitro anti-inflammatory action of 5,7,4'-trimethoxy-4-phenylcoumarin and 5,7-dimethoxy-4-phenylcoumarin produced by Streptomyces aureofaciens CMUAc130. The effects of the two coumarins were investigated on the formation of NO, PGE(2), and TNF-alpha and also on inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in lipopolysaccharide (LPS)-induced murine macrophage RAW 264.7 cells. The data obtained were consistent with the modulation of iNOS enzyme expression. A similar effect was also observed when LPS-induced PGE(2) release and COX-2 expression were tested. The inhibitory effects were shown in concentration-dependent manners. The 5,7,4'-Trimethoxy-4-phenylcoumarin and 5,7-dimethoxy-4-phenylcoumarin also mildly but significantly reduced the formation of TNF-alpha.
关键词	4-arylcoumarins Anti-inflammatory Activity Endophytic Streptomyces Murine Macrophage Raw 264.7 Cells
DOI	10.1080/08820130600992115
收录类别	SCI
语种	英语
WOS记录号	WOS:000245244700007
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/24813
专题	离退休
作者单位	1.Silpakorn Univ, Dept Microbiol, Fac Sci, Pathom 73000, Thailand 2.Silpakorn Univ, Dept Chem, Fac Sci, Pathom 73000, Thailand 3.Xiamen Univ, Sch Life Sci, Xiamen, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, Kunming, Peoples R China 5.Chiang Mai Univ, Fac Sci, Dept Biol, Chiang Mai 50000, Thailand 6.Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia
推荐引用方式 GB/T 7714	Taechowisan, Thongchai,Tuntiwachwuttikul, Pittaya,Lu, Chunhua,et al. Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009)[J]. IMMUNOLOGICAL INVESTIGATIONS,2007,36(2):203-211.
APA	Taechowisan, Thongchai,Tuntiwachwuttikul, Pittaya,Lu, Chunhua,Shen, Yuemao,Lumyong, Saisamorn,&Taylor, Walter C..(2007).Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009).IMMUNOLOGICAL INVESTIGATIONS,36(2),203-211.
MLA	Taechowisan, Thongchai,et al."Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009)".IMMUNOLOGICAL INVESTIGATIONS 36.2(2007):203-211.