| Six new C-21 steroidal glycosides from Asclepias curassavica L. |
| Li, JZ
; Liu, HY
; Lin, YJ
; Hao, XJ
; Ni, W
; Chen, CX
|
| 2008
|
| 发表期刊 | STEROIDS
 |
| ISSN | 0039-128X
|
| 卷号 | 73期号:6页码:594-600 |
| 摘要 | Six new C-21 steroidal glycosides, named curassavosides A-F (3-8), were obtained from the aerial parts of Asclepias curassavica (Asclepiadaceae), along with two known oxypregnanes, 12-O-benzoyldeacylmetaplexigenin (1) and 12-O-benzoylsarcostin (2). By spectroscopic methods, the structures of the six new compounds were determined as 12-O-benzoyldeacylmetaplexigenin 3-O-beta-D-oleandropyranosyl-(1-->4)-beta-D-digitoxopyranoside (3), 12-O-benzoylsarcostin 3-O-beta-D-oleandropyranosyl-(1-->4)-beta-D-digitoxopyranoside (4), sarcostin 3-O-beta-D-oleandropyranosyl-(1-->4)-beta-D-canaropyranosyl-(1-->4)-beta-D-oleandropyranosyl-(1-->4)-beta-D-digitoxopyranoside (5), sarcostin 3-O-beta-D-oleandropyranosyl-(1-->4)-beta-D-canaropyranosyl-(1-->4)-beta-D-canaropyranosyl-(1-->4)-beta-D-digitoxopyranoside (6), 12-O-benzoyldeacylmetaplexigenin 3-O-beta-D-glucopyranosyl-(1-->4)-beta-D-oleandropyranosyl-(1-->4)-beta-D-canaropyranosyl-(1-->4)-beta-D-oleandropyranosyl-(1-->4)-beta-D-digitoxopyrano side (7), and 12-O-benzoylsarcostin 3-O-beta-D-glucopyranosyl-(1-->4)-beta-D-oleandropyranosyl(1-->4)-beta-D-canaropyranosyl-(1-->4)-beta-D-oleandropyranosyl-(1-->4)-beta-D-digitoxopyranoside (8), respectively. All compounds (1-8) were tested for in vitro cytotoxicity; only compound 3 showed weak inhibitory activity against Raji and AGZY cell lines. (C) 2008 Elsevier Inc. All rights reserved. |
| 关键词 | Asclepias Curassavica
Asclepiadaceae
C-21 Steroidal Glycosides
|
| 学科领域 | Biochemistry & Molecular Biology
; Endocrinology & Metabolism
|
| 收录类别 | sci
|
| 语种 | English
|
| 文献类型 | 期刊论文
|
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/1849
|
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室
|
推荐引用方式
GB/T 7714 |
Li, JZ,Liu, HY,Lin, YJ,et al. Six new C-21 steroidal glycosides from Asclepias curassavica L.[J]. STEROIDS,2008,73(6):594-600.
|
| APA |
Li, JZ,Liu, HY,Lin, YJ,Hao, XJ,Ni, W,&Chen, CX.(2008).Six new C-21 steroidal glycosides from Asclepias curassavica L..STEROIDS,73(6),594-600.
|
| MLA |
Li, JZ,et al."Six new C-21 steroidal glycosides from Asclepias curassavica L.".STEROIDS 73.6(2008):594-600.
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