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题名: Cytotoxic prenylated xanthones from Calophyllum inophyllum
作者: Xiao, Qi1; Zeng, Yan-Bo1; Mei, Wen-Li1; Zhao, You-Xing2; Deng, Yuan-Yuan1; Dai, Hao-Fu1
刊名: JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
关键词: Calophyllum inophyllum ; cytotoxic activity ; prenylated xanthone ; caloxanthone N
英文摘要: A new prenylated xanthone (1), named caloxanthone N, together with two known constituents, gerontoxanthone C (2) and 2-hydroxyxanthone (3), was isolated from the ethanolic extract of the twigs of Calophyllum inophyllum. Their structures were completely elucidated using a combination of 1D, 2D NMR techniques (COSY, HMQC, HMBC, and ROESY) and HR-ESI-MS analyses. Compounds 1 and 2 exhibited cytotoxicity against chronic myelogenous leukemia cell line (K562) with IC50 values of 7.2 and 6.3gml-1, respectively.
出版日期: 2008
卷号: 10, 期号:10, 页码:993-997
DOI标识: 10.1080/10519990802240387
语种: 英语
收录类别: SCI ; IC
学科分类: Plant Sciences; Chemistry; Applied; Chemistry; Medicinal; Pharmacology & Pharmacy
ISSN号: 1028-6020
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/1729
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China

Recommended Citation:
Xiao, Q; Zeng, YB; Mei, WL; Zhao, YX; Deng, YY; Dai, HF.Cytotoxic prenylated xanthones from Calophyllum inophyllum,JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2008,10(10):993-997
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