Cytotoxic prenylated xanthones from Calophyllum inophyllum
Xiao, Qi1; Zeng, Yan-Bo1; Mei, Wen-Li1; Zhao, You-Xing2; Deng, Yuan-Yuan1; Dai, Hao-Fu1
AbstractA new prenylated xanthone (1), named caloxanthone N, together with two known constituents, gerontoxanthone C (2) and 2-hydroxyxanthone (3), was isolated from the ethanolic extract of the twigs of Calophyllum inophyllum. Their structures were completely elucidated using a combination of 1D, 2D NMR techniques (COSY, HMQC, HMBC, and ROESY) and HR-ESI-MS analyses. Compounds 1 and 2 exhibited cytotoxicity against chronic myelogenous leukemia cell line (K562) with IC50 values of 7.2 and 6.3gml-1, respectively.
KeywordCalophyllum Inophyllum Cytotoxic Activity Prenylated Xanthone Caloxanthone n
Subject AreaPlant Sciences ; Chemistry ; Applied ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
Indexed BySCI ; IC
WOS Research AreaPlant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000260798200016
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Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Affiliation1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
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GB/T 7714
Xiao, Qi,Zeng, Yan-Bo,Mei, Wen-Li,et al. Cytotoxic prenylated xanthones from Calophyllum inophyllum[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2008,10(10):993-997.
APA Xiao, Qi,Zeng, Yan-Bo,Mei, Wen-Li,Zhao, You-Xing,Deng, Yuan-Yuan,&Dai, Hao-Fu.(2008).Cytotoxic prenylated xanthones from Calophyllum inophyllum.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,10(10),993-997.
MLA Xiao, Qi,et al."Cytotoxic prenylated xanthones from Calophyllum inophyllum".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 10.10(2008):993-997.
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