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Jatropholane-Type Diterpenes from Euphorbia sikkimensis
Yang, Da-Song1,4; Zhang, You-Li2; Peng, Wei-Bing3; Wang, Li-Yan2; Li, Zi-Lei1,4; Wang, Xue3; Liu, Ke-Chun3; Yang, Yong-Ping1,4; Li, Hong-Lin2; Li, Xiao-Li1,4
Corresponding AuthorLi, HL (reprint author), E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China. ; hlli@ecust.edu.cn ; li_xiaoli11@mail.kib.ac.cn
2013-02-01
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume76Issue:2Pages:265-269
AbstractFour new jatropholane-type diterpenes (1-4), named sikkimenoids A-D, were isolated from the aerial parts of Euphorbia sikkimensis. The structural elucidations of 1-4 were accomplished by extensive NMR analyses, and their absolute configurations were established by ECD calculations. Compound 2 exhibited weak antiangiogenic activity with an IC50 value of 43.0 mu M when evaluated using a zebrafish model.
Subject AreaPlant Sciences ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
DOI10.1021/np300799n
Indexed BySCI ; IC
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000315431800019
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/16649
Collection中国科学院青藏高原研究所昆明部
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China
2.E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China
3.Shandong Acad Sci, Inst Biol, Jinan 250014, Peoples R China
4.Chinese Acad Sci, Kunming Inst Bot, Inst Tibetan Plateau Res Kunming, Kunming 650201, Peoples R China
Recommended Citation
GB/T 7714
Yang, Da-Song,Zhang, You-Li,Peng, Wei-Bing,et al. Jatropholane-Type Diterpenes from Euphorbia sikkimensis[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(2):265-269.
APA Yang, Da-Song.,Zhang, You-Li.,Peng, Wei-Bing.,Wang, Li-Yan.,Li, Zi-Lei.,...&Li, Xiao-Li.(2013).Jatropholane-Type Diterpenes from Euphorbia sikkimensis.JOURNAL OF NATURAL PRODUCTS,76(2),265-269.
MLA Yang, Da-Song,et al."Jatropholane-Type Diterpenes from Euphorbia sikkimensis".JOURNAL OF NATURAL PRODUCTS 76.2(2013):265-269.
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