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A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata
Shen, P; Wang, SL; Liu, XK; Yang, CR; Cai, B; Yao, XS
通讯作者yaoxinsheng@hotmail.com
2002-09-01
发表期刊CHINESE CHEMICAL LETTERS
ISSN1001-8417
卷号13期号:9页码:851-854
摘要Bioactivity-guided fractionation led to the isolation of a new steroidal saponin, orbiculatoside B, together with a pair of furostanol saponins, protobioside and methyl protobioside, from the fresh rhizomes of Dioscorea deltoidea Wall var. orbiculata. The new Compound was identified to be isonarthogenin 3 - O - alpha - L - rhamnopyranosyl (1-->2) - [alpha - L - rhamnopyranosyl - (1 --> 4)] - beta - D - glucopyranoside by various NMR techniques in combination with chemical methods. The three saponins showed strong activity against Pyricularia oryzae, and were cytotoxic to cancer cell line K562, HCT-15, A549, and A2780a in vitro.
关键词Dioscorea Deltoidea Wall Var. Orbiculata Orbiculatoside b Pyricularia Oryzae Cytotoxic
学科领域Chemistry, Multidisciplinary
收录类别SCI
语种英语
WOS记录号WOS:000178054700015
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14361
专题离退休
作者单位1.Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Beijing Inst Biomed, Beijing 100091, Peoples R China
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GB/T 7714
Shen, P,Wang, SL,Liu, XK,et al. A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata[J]. CHINESE CHEMICAL LETTERS,2002,13(9):851-854.
APA Shen, P,Wang, SL,Liu, XK,Yang, CR,Cai, B,&Yao, XS.(2002).A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata.CHINESE CHEMICAL LETTERS,13(9),851-854.
MLA Shen, P,et al."A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata".CHINESE CHEMICAL LETTERS 13.9(2002):851-854.
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