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Microsphaerones A and B, two novel gamma-pyrone derivatives from the sponge-derived fungus Microsphaeropsis sp.
Wang, CY; Wang, BG; Brauers, G; Guan, HS; Proksch, P; Ebel, R
2002-05-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号65期号:5页码:772-775
摘要Two new metabolites, microsphaerones A (1) and B (2), were identified from the EtOAc extract of the culture of an undescribed fungus of the genus Microsphaeropsis, isolated from the Mediterranean sponge Aplysina aerophoba. Compounds 1 and 2 represent the first examples of gamma-pyrone derivatives of the fungal genus Microsphaeropsis. The structures of the compounds were elucidated on the basis of comprehensive spectral analysis (H-1, C-13, H-1-H-1 COSY, HMQC, and HMBC NMR, as well as low- and high-resolution ESI and EIMS experiments). The (S)-2-methylsuccinic acid moiety present in 1 was established by GCMS analysis of a hydrolysis product.
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np0104828
收录类别IC ; SCI
语种英语
WOS记录号WOS:000175790500036
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14225
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作者单位1.Univ Dusseldorf, Inst Pharmazeut Biol, D-40225 Dusseldorf, Germany
2.Ocean Univ Qingdao, Marine Drug & Food Inst, Qingdao 266003, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Peoples R China
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Wang, CY,Wang, BG,Brauers, G,et al. Microsphaerones A and B, two novel gamma-pyrone derivatives from the sponge-derived fungus Microsphaeropsis sp.[J]. JOURNAL OF NATURAL PRODUCTS,2002,65(5):772-775.
APA Wang, CY,Wang, BG,Brauers, G,Guan, HS,Proksch, P,&Ebel, R.(2002).Microsphaerones A and B, two novel gamma-pyrone derivatives from the sponge-derived fungus Microsphaeropsis sp..JOURNAL OF NATURAL PRODUCTS,65(5),772-775.
MLA Wang, CY,et al."Microsphaerones A and B, two novel gamma-pyrone derivatives from the sponge-derived fungus Microsphaeropsis sp.".JOURNAL OF NATURAL PRODUCTS 65.5(2002):772-775.
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