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Cytotoxic pentacyclic triterpenoids from the rhizome of Astilbe chinensis
Hongxiang Sun; Jianxin Zhang; Yiping Ye; Yuanjiang Pan; Yueao Shen
2003
发表期刊HELVETICA CHIMICA ACTA
ISSN0018-019X
卷号86期号:7页码:2414-2423
摘要Guided by in vitro antineoplastic tests, four cytotoxic pentacyclic triterpenoids, 3beta-hydroxyolean-12-en-27-oic acid (1), 3beta-hydroxyurs-12-en-27-oic acid (2), 3beta,6beta-dihydroxyolean-12-en-27-oic acid (3), and 3beta-acetoxyolean-12-en-27-oic acid (4) were isolated from the rhizome of Astilbe chinensis. Their structures were determined on the basis of chemical evidence and extensive spectroscopic methods including one-dimensional and two-dimensional NMR. These compounds showed cytotoxic activities against HO-8910, Hela and HL60 cell lines. In addition, beta-sitosterol palmitate, daucosterol, and beta-sitosterol have also been isolated.
学科领域Chemistry, Multidisciplinary
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
WOS记录号WOS:000184797400010
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被引频次:29[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/13475
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GB/T 7714
Hongxiang Sun,Jianxin Zhang,Yiping Ye,et al. Cytotoxic pentacyclic triterpenoids from the rhizome of Astilbe chinensis[J]. HELVETICA CHIMICA ACTA,2003,86(7):2414-2423.
APA Hongxiang Sun,Jianxin Zhang,Yiping Ye,Yuanjiang Pan,&Yueao Shen.(2003).Cytotoxic pentacyclic triterpenoids from the rhizome of Astilbe chinensis.HELVETICA CHIMICA ACTA,86(7),2414-2423.
MLA Hongxiang Sun,et al."Cytotoxic pentacyclic triterpenoids from the rhizome of Astilbe chinensis".HELVETICA CHIMICA ACTA 86.7(2003):2414-2423.
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